Smoothened (Smo; green), a downstream effector of Hedgehog (Hh), is expressed in most cells of the wild-type Drosophila germarium including follicle stem cells, but is excluded from Boi- and Hh-expres...

Time-lapse experiments showing deltorphin II (100 nM; a selective agonist)-induced internalization of delta-opioid receptor–enhanced GFP (DOR-EGFP; green) receptors expressed in HEK 293 cells. The C...

Distribution of interneurons expressing EGFP from the 5HT3 receptor promoter (Tg(Htr3a-EGFP)DH30Gsat, www.gensat.org) in the dorsal hippocampus colabelled for the CB1 cannabinoid receptor (red) and co...

Distribution of interneurons expressing EGFP from the 5HT3 receptor promoter (Tg(Htr3a-EGFP)DH30Gsat, www.gensat.org) colabelled for the CB1 cannabinoid receptor. This image is from the pyramidal cel...

Time-lapse confocal experiment showing deltorphin II (100 nM; a selective agonist)-induced receptor internalization in primary caudate putamen neurons isolated from Oprd1-EGFP/EGFP knockin mouse. All ...

Time-lapse confocal experiment showing SNC80 (100 nM; a selective agonist)-induced receptor internalization in primary caudate putamen neurons isolated from Oprd1-EGFP/EGFP knockin mouse. All agonists...

Distribution of interneurons expressing EGFP from the 5HT3 receptor promoter (Tg(Htr3a-EGFP)DH30Gsat, www.gensat.org) in the ventral hippocampus colabelled for the CB1 cannabinoid receptor (red) and c...

Primary bone marrow macrophages derived from mouse plated on a coverslip and imaged live. Phase contrast microscopy allows us to see the dense f-actin rich leading edge, ruffles, mitochondria, the nu...

Primary bone marrow macrophages derived from mouse plated on a coverslip and imaged live. Internal Reflection Microscopy (IRM) shows direct apposition of the cells to coverslip with very little depth...

This animation shows the process of clathrin-mediated endocytosis of transferrin receptors, focusing on the assembly and disassembly of the clathrin cage. A single triskelion, which is approximately 1...